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프라그마틱 공식홈페이지 are studies designed to inform the practice of clinical trials in real life. They are often characterized as focusing on practical aspects of study design which include recruitment and consent, adherence and the use routinely available equipment.
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A pragmatic trial that uses a variety investigators and includes participants from various geographical regions is the Home Blood Pressure Management study (HBPM). This type of heterogeneity is essential for practical trials to be valid, and it also helps to reduce bias in the results. However, too much heterogeneity, can cause problems with the design of the trial.
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The aim of pragmatic trials is to replicate real-life scenarios and to achieve maximum validity externally. They are usually commissioned by practitioners and policy makers to inform their decision making. They can also be used to assess the cause-effect relationship of an intervention with its outcomes. However, they should not be used to replace explanation studies.
The idea of pragmatism is controversial, and there are questions about whether pragmatic trials should replace explanatory tests or if they are an addition to them. Schwartz and Lellouch1 made a distinction between explanatory studies, which confirm a physiological hypothesis or clinical hypothesis, as well as pragmatic trials, that inform the practice and policy decision-making. 프라그마틱 추천 proposed a framework called PRECIS for pragmatic trials.2 The tool was designed to define the characteristics of a pragmatic research study that includes the recruitment, design, and delivery of the intervention, and follow-up.
The number of pragmatic trials is increasing. A recent Medline search using the terms naturalistic and pragmatic, limited to randomized controlled trials (RCTs) produced 34 articles, as shown in red in Figure 2. This is a sign that the health science community is becoming increasingly sensitized to the subject of pragmatism. However, it is important to remember that the majority of these studies were conducted in primary care settings.